therapeutic tumor infiltrating lymphocytes

{
  "id": "MLC-T-ONC-017138",
  "term": "therapeutic tumor infiltrating lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of cells, consisting of autologous tumor infiltrating lymphocytes, that are manipulated in vitro and, upon administration in vivo, re-infiltrate the tumor to initiate tumor cell lysis. In vitro, therapeutic tumor-infiltrating lymphocytes (TILs) are isolated from tumor tissue and cultured with lymphokines such as interleukin-2; the therapeutic TILs are then infused into the patient, where, after re-infiltration of the tumor, they may induce lysis of tumor cells and tumor regression. The use of therapeutic TILs is considered a form of adoptive immunotherapy.",
  "synonyms": [
    "tumor infiltrating lymphocytes"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/therapeutic-tumor-infiltrating-lymphocytes/"
}