autologous tumor-infiltrating lymphocytes MDA-TIL

{
  "id": "MLC-T-ONC-011807",
  "term": "autologous tumor-infiltrating lymphocytes MDA-TIL",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous tumor-infiltrating lymphocytes (TILs) with potential antineoplastic activity. TILs are isolated from a patient’s tumor tissue, then cultured and expanded in vitro in the presence of interleukin-2 (IL-2) and an agonistic anti-4-1BB (CD137) antibody. Upon infusion of the autologous expanded TILs back into the patient, the cells specifically recognize, target, and kill the patient’s tumor cells.",
  "synonyms": [
    "MDA autologous tumor-infiltrating lymphocytes",
    "MDA autologous TILs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-tumor-infiltrating-lymphocytes-mda-til/"
}