toremifene citrate

{
  "id": "MLC-T-ONC-008765",
  "term": "toremifene citrate",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat postmenopausal women with breast cancer that has spread to other parts of the body. It is used in patients whose cancer is estrogen receptor positive (ER+) or when it is not known if the cancer is ER+ or estrogen receptor negative (ER-). Toremifene citrate blocks the effects of the hormone estrogen in breast tissue, which may help keep breast cancer cells from growing. It is a type of selective estrogen receptor modulator (SERM). Also called Fareston.",
    "The citrate salt of a nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which is manifested depending on the tissue or species."
  ],
  "synonyms": [
    "Fareston"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/toremifene-citrate/"
}