TORC1/2 kinase inhibitor DS-3078a

{
  "id": "MLC-T-ONC-017271",
  "term": "TORC1/2 kinase inhibitor DS-3078a",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable inhibitor of raptor-mTOR protein complex (TORC1) and rictor-mTOR protein complex (TORC2) with potential antineoplastic activity. TORC1/2 inhibitor DS-3078a binds to and inhibits both TORC1 and TORC2 , which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/torc1-2-kinase-inhibitor-ds-3078a/"
}