Transcription factor protein SON-DP

{
  "id": "MLC-T-ONC-017291",
  "term": "Transcription factor protein SON-DP",
  "field": "Oncology and biomedicine",
  "definition": "A transcription factor (TF) protein, with potential antineoplastic activity. Upon administration, TF protein SON-DP induces pluripotent reprogramming in cancer cells and generates transient induced pluripotent stem cells (tiPSCs). The in situ generated tiPSCs quickly re-differentiate into normal tissue cells. The tiPSCs also secrete exosomes, which provides embryonic stem cells (ESC)-like microenvironments. This may result in malignant phenotype reversion in the surrounding cancer cells. In addition, the tiPSCs may revert distant metastatic cancer cells into normal cells through tropism effect.",
  "synonyms": [
    "TF Protein SON-DP"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/transcription-factor-protein-son-dp/"
}