MLchartDataset catalogue

trifluridine

Term · Oncology and biomedicine · MLC-T-ONC-017323

A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.

Table 1. Record
IdentifierMLC-T-ONC-017323
FieldOncology and biomedicine
AbbreviationF3TdR
Synonymstriflorothymidine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-017323",
  "term": "trifluridine",
  "field": "Oncology and biomedicine",
  "definition": "A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.",
  "abbreviation": "F3TdR",
  "synonyms": [
    "triflorothymidine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/trifluridine/"
}

Record 16,715 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.