MLchartDataset catalogue

Tumor mutational burden

Term · Oncology and biomedicine · MLC-T-ONC-008969

The total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. Tumor mutational burden is being used as a type of biomarker. Also called TMB.

Table 1. Record
IdentifierMLC-T-ONC-008969
FieldOncology and biomedicine
SynonymsTMB
ReferencesNCI Dictionary of Cancer Terms
Record as JSON
{
  "id": "MLC-T-ONC-008969",
  "term": "Tumor mutational burden",
  "field": "Oncology and biomedicine",
  "definition": "The total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. Tumor mutational burden is being used as a type of biomarker. Also called TMB.",
  "synonyms": [
    "TMB"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/tumor-mutational-burden/"
}

Record 16,822 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.