Tumor mutational burden
Term · Oncology and biomedicine · MLC-T-ONC-008969
The total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. Tumor mutational burden is being used as a type of biomarker. Also called TMB.
| Identifier | MLC-T-ONC-008969 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | TMB |
| References | NCI Dictionary of Cancer Terms |
Record as JSON
{
"id": "MLC-T-ONC-008969",
"term": "Tumor mutational burden",
"field": "Oncology and biomedicine",
"definition": "The total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. Tumor mutational burden is being used as a type of biomarker. Also called TMB.",
"synonyms": [
"TMB"
],
"references": [
"NCI Dictionary of Cancer Terms"
],
"url": "https://mlchart.com/terminology/oncology/tumor-mutational-burden/"
}
Record 16,822 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.