MLchartDataset catalogue

TMB

Term · Oncology and biomedicine · MLC-T-ONC-008736

The total number of mutations (changes) found in the DNA of cancer cells. Knowing the TMB may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. TMB is being used as a type of biomarker. Also called tumor mutational burden.

Table 1. Record
IdentifierMLC-T-ONC-008736
FieldOncology and biomedicine
Expansionstumor mutational burden
ReferencesNCI Dictionary of Cancer Terms
Record as JSON
{
  "id": "MLC-T-ONC-008736",
  "term": "TMB",
  "field": "Oncology and biomedicine",
  "definition": "The total number of mutations (changes) found in the DNA of cancer cells. Knowing the TMB may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. TMB is being used as a type of biomarker. Also called tumor mutational burden.",
  "expansions": [
    "tumor mutational burden"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/tmb/"
}

Record 16,442 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.