vadimezan

{
  "id": "MLC-T-ONC-017444",
  "term": "vadimezan",
  "field": "Oncology and biomedicine",
  "definition": "A fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti-tumor activity of tumor-associated macrophages.",
  "abbreviation": "DMXAA",
  "synonyms": [
    "Dimethyloxoxanthene Acetic Acid"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/vadimezan/"
}