Velafermin

{
  "id": "MLC-T-ONC-009202",
  "term": "Velafermin",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance that is being studied in the prevention and treatment of oral mucositis (sores in the mouth) in patients receiving high-dose chemotherapy. Velafermin belongs to the family of drugs called recombinant human fibroblast growth factors (rhFGF).",
    "A recombinant human fibroblast growth factor-20 (rhFGF-20) protein with pro-proliferative activity. Velafermin stimulates DNA synthesis and cell proliferation, specifically promoting epithelial and mesenchymal cell proliferation, and may prevent radiation or chemotherapy-induced oral mucositis."
  ],
  "abbreviation": "rhFGF-20",
  "synonyms": [
    "recombinant human fibroblast growth factor-20",
    "rhFGF-20"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/velafermin/"
}