vindesine sulfate

{
  "id": "MLC-T-ONC-017507",
  "term": "vindesine sulfate",
  "field": "Oncology and biomedicine",
  "definition": "The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI)",
  "synonyms": [
    "desacetyl vinblastine amide sulfate",
    "vindesini sulfas",
    "vindesine sulphate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/vindesine-sulfate/"
}