vinorelbine tartrate emulsion

{
  "id": "MLC-T-ONC-017509",
  "term": "vinorelbine tartrate emulsion",
  "field": "Oncology and biomedicine",
  "definition": "An emulsion containing the tartrate salt of the semisynthetic vinca alkaloid vinorelbine with antineoplastic activity. Vinorelbine binds to tubulin, inhibiting tubulin polymerization into microtubules; cell division is prevented, the cell cycle is arrested metaphase and cell death ensues. In this formulation vinorelbine is emulsified in a homogeneous suspension of nanoparticles, which protects the venous endothelium from coming into direct contact with the active ingredient, potentially reducing vinorelbine-associated venous toxicity at the venous injection site.",
  "synonyms": [
    "vinorelbine tartrate injectable emulsion"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/vinorelbine-tartrate-emulsion/"
}