vitespen

{
  "id": "MLC-T-ONC-009294",
  "term": "vitespen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A vaccine made from a patient’s tumor cells that may help the body’s immune system kill cancer cells. This vaccine is used to treat kidney cancer, a type of brain cancer called glioma, and metastatic melanoma (a type of skin cancer that has spread). It is also being studied in the treatment of other types of cancer. Also called gp96 heat shock protein-peptide complex vaccine, gp96 HSP-peptide complex, and Oncophage.",
    "An autologous cancer vaccine derived from tumor-specific gp96 heat shock proteins. Heat shock proteins chaperone peptides through the endoplasmic reticulum, are key regulators of dendritic cell maturation, migration and antigen processing, and are involved in T-cell activation."
  ],
  "synonyms": [
    "gp96 heat shock protein-peptide complex vaccine",
    "gp96 HSP-peptide complex",
    "Oncophage",
    "heat shock protein peptide complex-96",
    "autologous gp96 heat shock protein peptide complex vaccine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/vitespen/"
}