X-linked dominant inheritance

{
  "id": "MLC-T-ONC-009414",
  "term": "X-linked dominant inheritance",
  "field": "Oncology and biomedicine",
  "definitions": [
    "One of the ways a genetic trait or condition caused by a mutated (changed) gene on the X chromosome can be passed down (inherited) from parent to child. In X-linked dominant inheritance, a genetic condition can occur when the child inherits one copy of a mutated (changed) gene on the X chromosome from one parent. Daughters have a 50% chance of inheriting the mutated X-linked gene from their mother and a 100% chance of inheriting the mutated X-linked gene from their father. Sons have a 50% chance of inheriting the mutated X-linked gene from their mother and a 0% chance of inheriting the mutated X-linked gene from their father.",
    "X-linked dominant inheritance refers to genetic conditions associated with mutations in genes on the X chromosome. A single copy of the mutation is enough to cause the disease in both males (who have one X chromosome) and females (who have two X chromosomes). In some conditions, the absence of a functional gene results in the death of affected males."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/x-linked-dominant-inheritance/"
}