X-linked recessive inheritance

{
  "id": "MLC-T-ONC-009415",
  "term": "X-linked recessive inheritance",
  "field": "Oncology and biomedicine",
  "definitions": [
    "One of the ways a genetic trait or condition caused by a mutated (changed) gene on the X chromosome can be passed down (inherited) from parent to child. In X-linked recessive inheritance, a daughter inherits a single mutated gene on the X chromosome from one of her parents. The X chromosome she inherits from the other parent will usually cancel the effect of the mutation, and she most likely will not have the genetic condition. If she inherits a mutated copy of the gene from both parents, she will be affected with the condition. Fathers cannot pass X-linked recessive conditions to their sons. When a son inherits a mutated gene on the X chromosome from his mother, the genetic condition is more likely to occur. X-linked recessive conditions most often occur in males.",
    "X-linked recessive inheritance refers to genetic conditions associated with mutations in genes on the X chromosome. A male carrying such a mutation will be affected, because he carries only one X chromosome. A female carrying a mutation in one gene, with a normal gene on the other X chromosome, is generally unaffected."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/x-linked-recessive-inheritance/"
}