Zoster vaccine recombinant, adjuvanted

{
  "id": "MLC-T-ONC-017715",
  "term": "Zoster vaccine recombinant, adjuvanted",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant, subunit herpes zoster (HZ) vaccine containing varicella-zoster virus (VZV) glycoprotein E (gE), that can potentially be used to prevent HZ infection, also called shingles. Upon administration, zoster vaccine recombinant, adjuvanted stimulates the host immune system to induce both specific CD4-positive T-cells and antibodies against VZV gE, thereby protecting against infection with HZ. VZV gE, the most common antigen in VZV viral particles, plays a key role in VZV infection. Compared to live-attenuated vaccines, the subunit vaccine prevents the risk of vaccine-induced HZ in immunocompromised patients.",
  "synonyms": [
    "herpes zoster vaccine 1437173A",
    "herpes zoster subunit vaccine GSK 1437173A",
    "HZ/su vaccine GSK 1437173A"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/zoster-vaccine-recombinant-adjuvanted/"
}