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Patent · US11679933B2 · B2 · US

Robotic processing system

(11) Publication number
US11679933B2
(21) Application number
17/362,056
(22) Filing date
2021-06-29
(30) Priority date
2018-02-02
(43) Publication date
2023-06-20
(45) Date of grant
2023-06-20
(51) IPC
B01L 9/02; B65G 47/90; B65G 69/28; G01N 35/00; G01N 35/04; B65G 1/06; B65G 1/12; B65G 1/133; G01N 35/02
(52) CPC
  • B65G Transport or storage devices, e.g. conveyors for loading or tipping, shop conveyor systems or pneumatic tube conveyors: 1/12, 1/06, 1/133, 2201/02, 47/905, 69/287
  • B01L Chemical or physical laboratory apparatus for general use: 9/02
  • G01N Investigating or analysing materials by determining their chemical or physical properties: 35/0099, 35/025, 35/04
(73) Assignee
HighRes Biosolutions Inc
(72) Inventors
Louis GUARRACINA; Ulysses Gilchrist
(54) Title
Robotic processing system
(57) Abstract

An automated biological or chemical sample processing system includes a dock frame and at least one dock frame module. The dock frame includes at least one docking interface that operably couples and interfaces the dock frame with laboratory equipment. The dock frame defines a spine structure of the system alongside which a variable number of laboratory equipment are arrayed. The dock frame extends longitudinally and has a variable elongated configuration and longitudinal length. The at least one dock frame module includes the docking interface, where each module is interchangeable with another module, and has control features with a predetermined relationship to a reference datum of the dock frame module and with a reference datum of the dock frame so that the at least one dock frame module is interchangeably coupled in linear configuration with at least the other dock frame module to select the variable elongated configuration and longitudinal length.

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Claims (23)

  1. A mobile storage array for storing climate controlled process samples in a facility space having different climate sections in the facility space each with different climates at least one of which is a controlled climate other than room habitation climate, the mobile storage array being movable as a unit in the facility space to the controlled climate section from another of the different climate sections, the mobile storage array comprising: a frame; and a storage carousel mounted to the frame and sized and shaped so that frame and storage carousel mounted thereto are movable as a unit, the storage carousel defining an array of holder storage racks, each disposed for storage therein of stacked sample holders, removably mounted to and distributed at a storage rack station, each storage rack station with a rack location, of the storage carousel; wherein the storage carousel has a selectably variable footprint and has a selectably variable total number of the storage rack stations forming the array, selectable between different numbers of more than one total storage rack stations by selectably adding or removing storage rack stations to the array so as to correspondingly increase or decrease the selected total number of storage rack stations from a first total number of the more than one total storage rack stations to a different second total number of the more than one total storage rack stations within a common enclosed perimeter of the carousel.
  2. The mobile storage array according to claim 1, wherein the selectably variable footprint of the storage carousel depends on a selected total number of the more than one total rack stations.
  3. The mobile storage array according to claim 1, wherein changing the total number of the more than one total storage rack stations from the first total number of the more than one total storage rack stations to the different second total number of the more than one total storage rack stations effects selection of the selectably variably footprint from a first selectable predetermined footprint size to a second selectable predetermined footprint size.
  4. The mobile storage array according to claim 3, wherein the first selectable predetermined footprint size corresponds to the first total number of the more than one total storage rack stations, and the second selectable predetermined footprint size corresponds to the second total number of the more than one total storage rack stations.
  5. The mobile storage array according to claim 3, wherein each of the different selectable total number of the more than one total storage rack stations defines a different corresponding predetermined footprint size of the carousel.
  6. The mobile storage array according to claim 1, wherein the storage rack at each of the storage rack stations is selectable from a number of different interchangeable storage rack modules at least one of which has a different predetermined storage characteristic, defining an in rack storage arrangement of sample holders, than another storage rack module from the number of different interchangeable storage rack modules.
  7. The mobile storage array according to claim 6, wherein the predetermined storage characteristic is a stacked storage holder capacity of the storage rack module, so that at least one of the different interchangeable storage rack modules has a different capacity of storage holders stacked therein than another capacity of storage holders stacked in another of the different interchangeable storage rack modules.
  8. The mobile storage array according to claim 6, wherein the predetermined storage characteristic is an in/out access opening configuration, disposed to access stacked storage holders in the storage rack module, which access opening is configured in at least one of the different interchangeable storage rack modules so as to provide for different access to the stacked storage holders than access provided by another opening configuration of another of the interchangeable storage rack modules.
  9. The mobile storage array according to claim 6, wherein each of the different interchangeable storage rack modules is configured so that each defines a corresponding storage rack station and storage rack, and respective coupling and decoupling of the selected different interchangeable storage rack modules to the storage carousel correspondingly adds and removes storage rack stations and storage racks to and from the storage carousel.
  10. The mobile storage array according to claim 1, wherein the mobile storage array further comprises a controller communicably connected to the storage carousel so as to register the selected total number of storage rack stations of the array, and a predetermined storage characteristic affecting storage arrangement of the interchangeable storage rack modules at each storage rack station of the total storage rack stations of the storage carousel.
  11. The mobile storage array according to claim 1, wherein the mobile storage array further comprises an articulated arm robot mounted to the frame so that the frame, the storage carousel and the articulated arm robot are movable as a unit, and wherein the articulated arm robot is configured so as to move relative to the frame so as to access, along at least one substantially horizontal axis, each storage holder in each storage rack module at each storage rack station of the storage carousel.
  12. The mobile storage array according to claim 1, wherein the storage carousel has a selectable number of different array modules stacked so to provide different array module levels, at least one of the array modules having the array of holder storage racks, and another of the different array modules having a different array of holder storage racks.
  13. The mobile storage array according to claim 1, wherein the selectably variable footprint of the storage carousel is sized so as to fit within the bounds of an enclosure that encloses the storage carousel.
  14. A storage array for storing climate controlled process samples in a controlled climate section of a facility, the storage array comprising: a frame; and a storage carousel movably mounted to the frame, the storage carousel defining an array of holder storage racks, each disposed for storage therein of stacked sample holders, removably mounted to and distributed at a storage rack station, each storage rack station with a rack location, of the carousel; wherein the storage carousel has a selectably variable footprint and has a selectably variable total number of the storage rack stations forming the array, selectable between different numbers of more than one total storage rack stations by selectably adding or removing storage rack stations to the array so as to correspondingly increase or decrease the selected total number of storage rack stations from a first total number of the more than one total storage rack stations to a different second total number of the more than one total storage rack stations within a common enclosed perimeter of the carousel.
  15. The storage array according to claim 14, wherein the selectably variable footprint of the storage carousel depends on a selected total number of the more than one total rack stations.
  16. The storage array according to claim 14, wherein changing the total number of the more than one total storage rack stations from the first total number of the more than one total storage rack stations to the different second total number of the more than one total storage rack stations effects selection of the selectably variably footprint from a first selectable predetermined footprint size to a second selectable predetermined footprint size.
  17. The storage array according to claim 16, wherein the first selectable predetermined footprint size corresponds to the first total number of the more than one total storage rack stations, and the second selectable predetermined footprint size corresponds to the second total number of the more than one total storage rack stations.
  18. The storage array according to claim 16, wherein each of the different selectable total number of the more than one total storage rack stations defines a different corresponding predetermined footprint size of the carousel.
  19. The storage array according to claim 14, wherein the storage rack at each of the storage rack stations is selectable from a number of different interchangeable storage rack modules at least one of which has a different predetermined storage characteristic, defining an in rack storage arrangement of sample holders, than another storage rack module from the number of different interchangeable storage rack modules.
  20. The storage array according to claim 19, wherein the predetermined storage characteristic is a stacked storage holder capacity of the storage rack module, so that at least one of the different interchangeable storage rack modules has a different capacity of storage holders stacked therein than another capacity of storage holders stacked in another of the different interchangeable storage rack modules.
  21. The storage array according to claim 19, wherein the predetermined storage characteristic is an in/out access opening configuration, disposed to access stacked storage holders in the storage rack module, which access opening is configured in at least one of the different interchangeable storage rack modules so as to provide for different access to the stacked storage holders than access provided by another opening configuration of another of the interchangeable storage rack modules.
  22. The storage array according to claim 19, wherein each of the different interchangeable storage rack modules is configured so that each defines a corresponding storage rack station and storage rack, and respective coupling and decoupling of the selected different interchangeable storage rack modules to the storage carousel correspondingly adds and removes storage rack stations and storage racks to and from the storage carousel.
  23. The storage array according to claim 14, wherein the mobile storage array further comprises a controller communicably connected to the storage carousel so as to register the selected total number of storage rack stations of the array, and a predetermined storage characteristic affecting storage arrangement of the storage rack modules at each storage rack station of the total storage rack stations of the storage carousel.

Description

The aspects of the disclosed embodiment described herein generally relate to life sciences equipment, and more particularly, to automated handling and processing of life sciences processing equipment.

High throughput screening is a well-known form of scientific experimentation in the life sciences industry which enables a research facility to conduct a large quantity of experiments at the same time. In one form of high throughput screening which is well-known in the art, a plate is provided which includes a large number of isolated, miniaturized wells (e.g., 96, 384, or 1536 wells per plate), whereby a unique compound is disposed in each well. An array of different substances is then disposed within each well where a reaction between the compound and substances may be discovered. In this manner, high throughput screening can be used to subject a particular substance to an entire library of compounds at the same time and, as a result, is highly useful in the discover of, e.g., new medicines, vaccines, and biopharmaceuticals.

High throughput screening is generally performed in an environmentally controllable enclosure which is commonly referred to as a cell or chamber. These cells may provide a researcher with an enclosed environment that is most suitable for laboratory testing. High throughput screening also, generally relies on automation to conduct assays which are otherwise repetitive in nature. Various types of laboratory automation tools are presently used in conjunction with high throughput screening.

Citations (24)

  • US6477442B1
  • WO2001003841A1
  • US20040175258A1
  • US7670553B2
  • US7832921B2
  • US20090240370A1
  • WO2008007923A1
  • US20090035181A1
  • US20090003981A1
  • US20090302795A1
  • US20130280143A1
  • US9561590B1
  • US20150120050A1
  • US20150203297A1
  • WO2016061471A1
  • US20170217027A1
  • US20160200514A1
  • US20160238627A1
  • WO2016178351A1
  • EP3292961A1
  • US20180133893A1
  • WO2017014999A1
  • US20180202908A1
  • US20200122328A1
Record as JSON
{
  "publication_number": "US11679933B2",
  "country": "US",
  "kind": "B2",
  "title": "Robotic processing system",
  "abstract": "An automated biological or chemical sample processing system includes a dock frame and at least one dock frame module. The dock frame includes at least one docking interface that operably couples and interfaces the dock frame with laboratory equipment. The dock frame defines a spine structure of the system alongside which a variable number of laboratory equipment are arrayed. The dock frame extends longitudinally and has a variable elongated configuration and longitudinal length. The at least one dock frame module includes the docking interface, where each module is interchangeable with another module, and has control features with a predetermined relationship to a reference datum of the dock frame module and with a reference datum of the dock frame so that the at least one dock frame module is interchangeably coupled in linear configuration with at least the other dock frame module to select the variable elongated configuration and longitudinal length.",
  "claims": [
    "1. A mobile storage array for storing climate controlled process samples in a facility space having different climate sections in the facility space each with different climates at least one of which is a controlled climate other than room habitation climate, the mobile storage array being movable as a unit in the facility space to the controlled climate section from another of the different climate sections, the mobile storage array comprising: a frame; and a storage carousel mounted to the frame and sized and shaped so that frame and storage carousel mounted thereto are movable as a unit, the storage carousel defining an array of holder storage racks, each disposed for storage therein of stacked sample holders, removably mounted to and distributed at a storage rack station, each storage rack station with a rack location, of the storage carousel; wherein the storage carousel has a selectably variable footprint and has a selectably variable total number of the storage rack stations forming the array, selectable between different numbers of more than one total storage rack stations by selectably adding or removing storage rack stations to the array so as to correspondingly increase or decrease the selected total number of storage rack stations from a first total number of the more than one total storage rack stations to a different second total number of the more than one total storage rack stations within a common enclosed perimeter of the carousel.",
    "2. The mobile storage array according to claim 1, wherein the selectably variable footprint of the storage carousel depends on a selected total number of the more than one total rack stations.",
    "3. The mobile storage array according to claim 1, wherein changing the total number of the more than one total storage rack stations from the first total number of the more than one total storage rack stations to the different second total number of the more than one total storage rack stations effects selection of the selectably variably footprint from a first selectable predetermined footprint size to a second selectable predetermined footprint size.",
    "4. The mobile storage array according to claim 3, wherein the first selectable predetermined footprint size corresponds to the first total number of the more than one total storage rack stations, and the second selectable predetermined footprint size corresponds to the second total number of the more than one total storage rack stations.",
    "5. The mobile storage array according to claim 3, wherein each of the different selectable total number of the more than one total storage rack stations defines a different corresponding predetermined footprint size of the carousel.",
    "6. The mobile storage array according to claim 1, wherein the storage rack at each of the storage rack stations is selectable from a number of different interchangeable storage rack modules at least one of which has a different predetermined storage characteristic, defining an in rack storage arrangement of sample holders, than another storage rack module from the number of different interchangeable storage rack modules.",
    "7. The mobile storage array according to claim 6, wherein the predetermined storage characteristic is a stacked storage holder capacity of the storage rack module, so that at least one of the different interchangeable storage rack modules has a different capacity of storage holders stacked therein than another capacity of storage holders stacked in another of the different interchangeable storage rack modules.",
    "8. The mobile storage array according to claim 6, wherein the predetermined storage characteristic is an in/out access opening configuration, disposed to access stacked storage holders in the storage rack module, which access opening is configured in at least one of the different interchangeable storage rack modules so as to provide for different access to the stacked storage holders than access provided by another opening configuration of another of the interchangeable storage rack modules.",
    "9. The mobile storage array according to claim 6, wherein each of the different interchangeable storage rack modules is configured so that each defines a corresponding storage rack station and storage rack, and respective coupling and decoupling of the selected different interchangeable storage rack modules to the storage carousel correspondingly adds and removes storage rack stations and storage racks to and from the storage carousel.",
    "10. The mobile storage array according to claim 1, wherein the mobile storage array further comprises a controller communicably connected to the storage carousel so as to register the selected total number of storage rack stations of the array, and a predetermined storage characteristic affecting storage arrangement of the interchangeable storage rack modules at each storage rack station of the total storage rack stations of the storage carousel.",
    "11. The mobile storage array according to claim 1, wherein the mobile storage array further comprises an articulated arm robot mounted to the frame so that the frame, the storage carousel and the articulated arm robot are movable as a unit, and wherein the articulated arm robot is configured so as to move relative to the frame so as to access, along at least one substantially horizontal axis, each storage holder in each storage rack module at each storage rack station of the storage carousel.",
    "12. The mobile storage array according to claim 1, wherein the storage carousel has a selectable number of different array modules stacked so to provide different array module levels, at least one of the array modules having the array of holder storage racks, and another of the different array modules having a different array of holder storage racks.",
    "13. The mobile storage array according to claim 1, wherein the selectably variable footprint of the storage carousel is sized so as to fit within the bounds of an enclosure that encloses the storage carousel.",
    "14. A storage array for storing climate controlled process samples in a controlled climate section of a facility, the storage array comprising: a frame; and a storage carousel movably mounted to the frame, the storage carousel defining an array of holder storage racks, each disposed for storage therein of stacked sample holders, removably mounted to and distributed at a storage rack station, each storage rack station with a rack location, of the carousel; wherein the storage carousel has a selectably variable footprint and has a selectably variable total number of the storage rack stations forming the array, selectable between different numbers of more than one total storage rack stations by selectably adding or removing storage rack stations to the array so as to correspondingly increase or decrease the selected total number of storage rack stations from a first total number of the more than one total storage rack stations to a different second total number of the more than one total storage rack stations within a common enclosed perimeter of the carousel.",
    "15. The storage array according to claim 14, wherein the selectably variable footprint of the storage carousel depends on a selected total number of the more than one total rack stations.",
    "16. The storage array according to claim 14, wherein changing the total number of the more than one total storage rack stations from the first total number of the more than one total storage rack stations to the different second total number of the more than one total storage rack stations effects selection of the selectably variably footprint from a first selectable predetermined footprint size to a second selectable predetermined footprint size.",
    "17. The storage array according to claim 16, wherein the first selectable predetermined footprint size corresponds to the first total number of the more than one total storage rack stations, and the second selectable predetermined footprint size corresponds to the second total number of the more than one total storage rack stations.",
    "18. The storage array according to claim 16, wherein each of the different selectable total number of the more than one total storage rack stations defines a different corresponding predetermined footprint size of the carousel.",
    "19. The storage array according to claim 14, wherein the storage rack at each of the storage rack stations is selectable from a number of different interchangeable storage rack modules at least one of which has a different predetermined storage characteristic, defining an in rack storage arrangement of sample holders, than another storage rack module from the number of different interchangeable storage rack modules.",
    "20. The storage array according to claim 19, wherein the predetermined storage characteristic is a stacked storage holder capacity of the storage rack module, so that at least one of the different interchangeable storage rack modules has a different capacity of storage holders stacked therein than another capacity of storage holders stacked in another of the different interchangeable storage rack modules.",
    "21. The storage array according to claim 19, wherein the predetermined storage characteristic is an in/out access opening configuration, disposed to access stacked storage holders in the storage rack module, which access opening is configured in at least one of the different interchangeable storage rack modules so as to provide for different access to the stacked storage holders than access provided by another opening configuration of another of the interchangeable storage rack modules.",
    "22. The storage array according to claim 19, wherein each of the different interchangeable storage rack modules is configured so that each defines a corresponding storage rack station and storage rack, and respective coupling and decoupling of the selected different interchangeable storage rack modules to the storage carousel correspondingly adds and removes storage rack stations and storage racks to and from the storage carousel.",
    "23. The storage array according to claim 14, wherein the mobile storage array further comprises a controller communicably connected to the storage carousel so as to register the selected total number of storage rack stations of the array, and a predetermined storage characteristic affecting storage arrangement of the storage rack modules at each storage rack station of the total storage rack stations of the storage carousel."
  ],
  "description_excerpt": "The aspects of the disclosed embodiment described herein generally relate to life sciences equipment, and more particularly, to automated handling and processing of life sciences processing equipment.\n\nHigh throughput screening is a well-known form of scientific experimentation in the life sciences industry which enables a research facility to conduct a large quantity of experiments at the same time. In one form of high throughput screening which is well-known in the art, a plate is provided which includes a large number of isolated, miniaturized wells (e.g., 96, 384, or 1536 wells per plate), whereby a unique compound is disposed in each well. An array of different substances is then disposed within each well where a reaction between the compound and substances may be discovered. In this manner, high throughput screening can be used to subject a particular substance to an entire library of compounds at the same time and, as a result, is highly useful in the discover of, e.g., new medicines, vaccines, and biopharmaceuticals.\n\nHigh throughput screening is generally performed in an environmentally controllable enclosure which is commonly referred to as a cell or chamber. These cells may provide a researcher with an enclosed environment that is most suitable for laboratory testing. High throughput screening also, generally relies on automation to conduct assays which are otherwise repetitive in nature. Various types of laboratory automation tools are presently used in conjunction with high throughput screening.",
  "cpc": [
    "B65G 1/12",
    "B01L 9/02",
    "B65G 1/06",
    "B65G 1/133",
    "B65G 2201/02",
    "B65G 47/905",
    "B65G 69/287",
    "G01N 35/0099",
    "G01N 35/025",
    "G01N 35/04"
  ],
  "ipc": [
    "B01L 9/02",
    "B65G 47/90",
    "B65G 69/28",
    "G01N 35/00",
    "G01N 35/04",
    "B65G 1/06",
    "B65G 1/12",
    "B65G 1/133",
    "G01N 35/02"
  ],
  "assignees": [
    "HighRes Biosolutions Inc"
  ],
  "inventors": [
    "Louis GUARRACINA",
    "Ulysses Gilchrist"
  ],
  "filing_date": "2021-06-29",
  "publication_date": "2023-06-20",
  "grant_date": "2023-06-20",
  "priority_date": "2018-02-02",
  "application_number": "US-202117362056-A",
  "family_id": "67475393",
  "cited_by_count": 14,
  "citations": [
    "US6477442B1",
    "WO2001003841A1",
    "US20040175258A1",
    "US7670553B2",
    "US7832921B2",
    "US20090240370A1",
    "WO2008007923A1",
    "US20090035181A1",
    "US20090003981A1",
    "US20090302795A1",
    "US20130280143A1",
    "US9561590B1",
    "US20150120050A1",
    "US20150203297A1",
    "WO2016061471A1",
    "US20170217027A1",
    "US20160200514A1",
    "US20160238627A1",
    "WO2016178351A1",
    "EP3292961A1",
    "US20180133893A1",
    "WO2017014999A1",
    "US20180202908A1",
    "US20200122328A1"
  ]
}

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