Synthetic absorbable surgical devices of poly(alkylene oxalates)

{
  "publication_number": "US4205399A",
  "country": "US",
  "kind": "A",
  "title": "Synthetic absorbable surgical devices of poly(alkylene oxalates)",
  "abstract": "Synthetic filaments composed of homopolymers and copolymers of poly(alkylene oxalates) are absorbable in animal tissue with minimal adverse tissue reaction. Polymers prepared by reacting a dialkyl oxalate with an alkylene diol are melt spun and drawn to obtain oriented fibers having good tensile properties and a high level of flexibility and softness. The filaments are particularly useful in the preparation of surgical prosthesis comprising woven or knitted fabrics and meshes. Other absorbable surgical devices including films and molded items may also be prepared from the disclosed polymer.",
  "claims": [
    "1. A surgical prosthesis comprising a fabric manufactured at least in part from synthetic absorbable fibers comprising a polymer having a major portion of units of the formula ##STR3## wherein R is a C 3 to C 16 alkylene and n is the degree of polymerization resulting in a fiber-forming polymer having an inherent viscosity of at least about 0.4 as determined at 25° C. on a 0.1 percent solution of polymer in chloroform or hexafluoroisopropanol.",
    "2. A surgical prosthesis of claim 1 wherein said fibers are further characterized by a straight tensile strength of at least about 30,000 psi and a Young's modulus of less than about 600,000 psi.",
    "3. A surgical prosthesis of claim 2 wherein said polymer is a homopolymer of poly(alkylene oxalate) or a copolymer of C 3 to C 16 alkylene oxalate with up to about 50 percent by weight of at least one other monomer copolymerizable to an absorbable polymer.",
    "4. A surgical prosthesis of claim 1 comprising a woven fabric.",
    "5. A surgical prosthesis of claim 1 comprising a knitted fabric.",
    "6. A surgical prosthesis of claim 1 comprising a nonwoven, felted fabric.",
    "7. A surgical prosthesis of claim 1 comprising a tubular vascular prosthetic device.",
    "8. A surgical prosthesis comprising a solid surgical aid, cast or machined from an absorbable polymer having a major portion of units of the formula ##STR4## wherein R is a C 3 to C 16 alkylene and n is the degree of polymerization resulting in a polymer having an inherent viscosity of at least 0.4 determined at 25° C. on a 0.1 percent solution of polymer in chloroform or hexafluoroisopropanol.",
    "9. A surgical prosthesis of claim 8 wherein said polymer is a homopolymer of poly(alkylene oxalate) or a copolymer of C 3 to C 16 alkylene oxalate with up to about 50 percent by weight of at least one other monomer copolymerizable to an absorbable polymer."
  ],
  "cpc": [
    "D01F 6/84",
    "A61L 17/105",
    "A61L 27/18",
    "C08G 63/16",
    "D01F 6/625"
  ],
  "assignees": [
    "ETHICON INC"
  ],
  "filing_date": "1978-05-26",
  "publication_date": "1980-06-03",
  "grant_date": "1980-06-03",
  "priority_date": "1977-06-13",
  "application_number": "US-91004278-A",
  "family_id": "27122842",
  "citations": [
    "US4032993A",
    "US4105034A"
  ]
}