Complete genome sequence of the methanogen Methanobrevibacter ruminantium

{
  "publication_number": "US9441016B2",
  "country": "US",
  "kind": "B2",
  "title": "Complete genome sequence of the methanogen Methanobrevibacter ruminantium",
  "abstract": "The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.",
  "claims": [
    "1. A vaccine composition comprising an adjuvant, and a polypeptide comprising the amino acid sequence SEQ ID NO: 7555.",
    "2. The vaccine composition of claim 1, wherein the polypeptide comprises a conjugate or fusion molecule.",
    "3. The vaccine composition of claim 1, wherein the vaccine composition is an animal vaccine composition against a methanogen.",
    "4. The vaccine composition of claim 3, wherein the methanogen is Methanobrevibacter ruminantium.",
    "5. The vaccine composition of claim 3, wherein the animal is a ruminant.",
    "6. The vaccine composition of claim 5, wherein the ruminant is selected from the group consisting of cattle, sheep, goats, buffalo, moose, antelope, caribou, and deer.",
    "7. The vaccine composition of claim 1, wherein the vaccine composition is a ruminant vaccine composition for use in reducing methane emissions.",
    "8. A kit for reducing methanogen growth or methane production in a ruminant comprising the vaccine composition of claim 1.",
    "9. A method of vaccinating an animal against a methanogen, comprising the step of administering to said animal, the vaccine composition according to claim 1.",
    "10. The method of claim 9, wherein the methanogen is Methanobrevibacter ruminantium.",
    "11. The method of claim 9 wherein the animal is a ruminant.",
    "12. The method of claim 11, wherein the ruminant is selected from the group consisting of cattle, sheep, goats, buffalo, moose, antelope, caribou, and deer.",
    "13. A method of reducing methane emissions from a ruminant, comprising vaccinating the ruminant against a methanogen according to claim 9."
  ],
  "cpc": [
    "C07K 14/195",
    "A61K 2039/552",
    "A61K 39/0001",
    "C07K 16/1267",
    "C12N 15/74",
    "G01N 2333/195",
    "Y02E 50/10",
    "Y02E 50/30",
    "Y02P 60/22"
  ],
  "assignees": [
    "ALTERMANN ERIC HEINZ",
    "ATTWOOD GRAEME TREVOR",
    "COOK GREGORY",
    "DEY DEBJIT",
    "FERGUSON SCOTT A",
    "JANSSEN PETRUS HENDRICUS",
    "KELLY WILLIAM JOHN",
    "KONG ZHANHAO",
    "LAMBIE SUZANNE",
    "LEAHY SINEAD CHRISTINE",
    "LI DONG",
    "MCMILLAN DUNCAN",
    "MCTAVISH SHARLA",
    "PACHECO DIANA",
    "RONIMUS ROBERT STARR",
    "SANG CARRIE",
    "YEOMAN CARL",
    "PASTORAL GREENHOUSE GAS RES LTD"
  ],
  "filing_date": "2010-08-27",
  "publication_date": "2016-09-13",
  "grant_date": "2016-09-13",
  "priority_date": "2009-08-27",
  "application_number": "US-201013392075-A",
  "family_id": "43628216",
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}