Method of making pressure-sensitive adhesive article including active agent

{
  "publication_number": "US9592161B2",
  "country": "US",
  "kind": "B2",
  "title": "Method of making pressure-sensitive adhesive article including active agent",
  "abstract": "A method includes contact printing an active composition onto a surface of a release substrate to form a printed surface. The active composition spontaneously dewets the surface of the release substrate to form active deposits on the surface of the release substrate. The active composition comprises an active agent dissolved or dispersed in an aqueous liquid vehicle. A pressure-sensitive adhesive layer is disposed on the printed surface.",
  "claims": [
    "1. A method of making a pressure-sensitive adhesive article, the method comprising: contact printing an active composition onto a surface of a release substrate to form a printed surface, whereby the active composition spontaneously dewets the surface of the release substrate to form active deposits on the surface of the release substrate, wherein the active composition comprises an active agent dissolved or dispersed in an aqueous liquid vehicle; and disposing a pressure-sensitive adhesive layer on the printed surface.",
    "2. The method of claim 1, wherein, as initially contacted with the surface of the release substrate, the active composition contacts a first area of the surface of the release substrate, and wherein the active deposits contact a second area of the surface of the release substrate, and wherein the second area is less than or equal to 50 percent of the first area.",
    "3. The method of claim 1, wherein the active composition further comprises a hydratable polymer.",
    "4. The method of claim 1, wherein the active agent comprises at least one non-volatile component.",
    "5. The method of claim 1, wherein the active agent comprises at least one of an antimicrobial agent, a topical antiseptic, or a cationic antiseptic.",
    "6. The method of claim 1, wherein the active agent comprises chlorhexidine gluconate.",
    "7. The method of claim 1, wherein the active agent comprises a polymer.",
    "8. The method of claim 1, wherein the surface of the release substrate comprises at least one of a silicone polymer, fluoropolymer, or acrylic polymer.",
    "9. The method of claim 1, wherein the surface of the release substrate is microstructured.",
    "10. The method of claim 1, wherein the active deposits are arranged in an array on the surface of the release substrate.",
    "11. The method of claim 1, wherein the contact printing comprises flexographic printing.",
    "12. The method of claim 1, wherein the contact printing comprises gravure roll coating.",
    "13. The method of claim 1, wherein the contact printing comprises knife coating or doctor blade coating.",
    "14. The method of claim 1, further comprising removing at least a portion of the liquid vehicle from the active composition after it is contact printed onto the surface of the release substrate, but before the pressure-sensitive adhesive layer is disposed on the printed surface.",
    "15. The method of claim 1, wherein, prior to contacting the surface of the release substrate, the pressure-sensitive adhesive is disposed on a backing.",
    "16. The method of claim 15, wherein at least a portion of the backing is transparent or translucent.",
    "17. The method of claim 15, wherein at least a portion of the backing and at least a portion of the pressure-sensitive adhesive layer are transparent or translucent.",
    "18. The method of claim 1, wherein the pressure-sensitive layer is formed by coating a pressure-sensitive adhesive composition on the printed surface."
  ],
  "description_excerpt": "The present disclosure relates broadly to pressure-sensitive adhesive articles and methods for their manufacture.\n\nWound care articles such as, for example, wound dressings and incise drapes are available in a variety of designs to protect wounds and surgical incisions from infection. Such articles are commonly adhered to the skin of patients by a pressure-sensitive adhesive (PSA) layer. Typically, the PSA layer is disposed on a substrate such as a flexible film, foam, woven materials, non-woven materials, or gauze. To reduce risk of infection, antimicrobial material (e.g., material including an antimicrobial compound) has been used in combination with the PSA layer.\n\nIn one aspect, the present disclosure provides a method of making a pressure-sensitive adhesive article, the method comprising:\n\ncontact printing an active composition onto a surface of a release substrate to form a printed surface, whereby the active composition spontaneously dewets the surface of the release substrate to form active deposits on the surface of the release substrate, wherein the active composition comprises an active agent dissolved or dispersed in an aqueous liquid vehicle; and\n\ndisposing a pressure-sensitive adhesive layer on the printed surface.\n\nMethods according to the present disclosure are useful; for example, to prepare adhesive articles having active agents incorporated therein.\n\nNon-contact methods such as inkjet printing may be unreliable for some fluid solutions due to problems such as nozzle clogging and/or corrosion, and can be relatively slow.",
  "cpc": [
    "A61F 13/0283",
    "A61F 13/025",
    "A61F 13/0289",
    "A61K 9/7038",
    "A61L 15/26",
    "A61L 15/44",
    "A61L 2300/20",
    "A61L 2300/606",
    "C08K 2201/013",
    "C08K 5/0058",
    "C08L 2203/02",
    "C09J 2201/28",
    "C09J 2301/204",
    "C09J 2429/00",
    "C09J 7/0207",
    "C09J 7/38"
  ],
  "ipc": [
    "A61F 13/02",
    "A61K 9/70",
    "A61L 15/26",
    "A61L 15/44",
    "C09J 7/38",
    "B05D 5/10"
  ],
  "assignees": [
    "3M Innovative Properties Co"
  ],
  "inventors": [
    "Joseph D. Rule",
    "Jeffrey H. Tokie",
    "Kim B. Saulsbury",
    "Deena M. Conrad-Vlasak",
    "Kanta Kumar"
  ],
  "filing_date": "2012-12-10",
  "publication_date": "2017-03-14",
  "grant_date": "2017-03-14",
  "priority_date": "2011-12-13",
  "application_number": "US-201214363444-A",
  "family_id": "47430117",
  "cited_by_count": 12,
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}