Chromatin immunoprecipitation

{
  "id": "MLC-T-AGR-001298",
  "term": "Chromatin immunoprecipitation",
  "field": "Agriculture and food",
  "definition": "A technique for identifying specific DNA sequences that are bound, in vivo, to proteins of interest. It involves formaldehyde fixation of chromatin to crosslink the dna-binding proteins to the DNA. After shearing the DNA into small fragments, specific DNA-protein complexes are isolated by immunoprecipitation with protein-specific antibodies. Then, the DNA isolated from the complex can be identified by PCR amplification and sequencing.",
  "synonyms": [
    "chromatin immunoprecipitation sequencing"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "precipitin tests"
  ],
  "references": [
    "Medical Subject Headings",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "inmunoprecipitación de la cromatina"
  },
  "url": "https://mlchart.com/terminology/agriculture/chromatin-immunoprecipitation/"
}