Chromatin immunoprecipitation

{
  "id": "MLC-T-CHM-002042",
  "term": "Chromatin immunoprecipitation",
  "field": "Chemistry",
  "definition": "A molecular biology technique used to study the association between specific proteins and DNA segments within a cell. This method involves cross-linking proteins to DNA, fragmenting the chromatin, and then using antibodies to selectively precipitate the protein-DNA complexes. The isolated DNA can then be analyzed to identify the genomic regions bound by the protein of interest.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "amplification of deoxyribonucleic acid",
    "immunoprecipitation"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1183 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/chromatin-immunoprecipitation/"
}