Immunoprecipitation
Term · Chemistry · MLC-T-CHM-005700
A technique used to isolate and concentrate a specific protein or protein complex from a solution using an antibody that binds specifically to that protein. The antibody-protein complex is then precipitated out of solution, often by binding to an insoluble support like protein A/G beads. This method is widely employed for studying protein-protein interactions, post-translational modifications, and protein abundance.
| Identifier | MLC-T-CHM-005700 |
|---|---|
| Field | Chemistry |
| Subject | Analytical Chemistry |
| References | PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1140 (https://doi.org/10.1515/pac-2016-1120) |
Record as JSON
{
"id": "MLC-T-CHM-005700",
"term": "Immunoprecipitation",
"field": "Chemistry",
"definition": "A technique used to isolate and concentrate a specific protein or protein complex from a solution using an antibody that binds specifically to that protein. The antibody-protein complex is then precipitated out of solution, often by binding to an insoluble support like protein A/G beads. This method is widely employed for studying protein-protein interactions, post-translational modifications, and protein abundance.",
"subject": "Analytical Chemistry",
"references": [
"PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1140 (https://doi.org/10.1515/pac-2016-1120)"
],
"url": "https://mlchart.com/terminology/chemistry/immunoprecipitation/"
}
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