Footprinting

{
  "id": "MLC-T-CHM-004584",
  "term": "Footprinting",
  "field": "Chemistry",
  "definition": "A molecular biology technique used to identify the specific binding sites of proteins on DNA or RNA molecules. It involves treating a nucleic acid-protein complex with a nuclease or chemical agent, followed by analysis of the protected regions. This method reveals the precise sequence of nucleotides that are physically protected by the bound protein.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "exometabolome"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1167 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/footprinting/"
}