comet assay
Term · Agriculture and food · MLC-T-AGR-001422
A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
| Identifier | MLC-T-AGR-001422 |
|---|---|
| Field | Agriculture and food |
| Subject | Animals, Livestock, One Health |
| Synonyms | single cell gel electrophoresis assay; single-cell gel electrophoresis |
| References | Medical Subject Headings 2017; NAL Agricultural Thesaurus and Glossary |
| See also | agar gel electrophoresis; Ames test; DNA fragmentation; DNA damage |
| Translations | Spanish: ensayo cometa |
Record as JSON
{
"id": "MLC-T-AGR-001422",
"term": "comet assay",
"field": "Agriculture and food",
"definition": "A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a \"comet with tail\" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.",
"synonyms": [
"single cell gel electrophoresis assay",
"single-cell gel electrophoresis"
],
"subject": "Animals, Livestock, One Health",
"see_also": [
"agar gel electrophoresis",
"Ames test",
"DNA fragmentation",
"DNA damage"
],
"references": [
"Medical Subject Headings 2017",
"NAL Agricultural Thesaurus and Glossary"
],
"translations": {
"es": "ensayo cometa"
},
"url": "https://mlchart.com/terminology/agriculture/comet-assay/"
}
Record 1,422 of 6,908 in Agriculture and food terminology (MLC-0114). Request the full dataset.