epidermal growth factor receptors

{
  "id": "MLC-T-AGR-002246",
  "term": "epidermal growth factor receptors",
  "field": "Agriculture and food",
  "definition": "A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for epidermal growth factor and EGF related peptides including transforming growth factor alpha, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.",
  "synonyms": [
    "EGF receptor",
    "EGFR protein",
    "TGF-alpha receptor",
    "c-erbB-1 protein",
    "epidermal growth factor receptor kinase",
    "epidermal growth factor receptor protein-tyrosine kinase",
    "epidermal growth factor-urogastrone receptor",
    "erbB-1 proto-oncogene protein",
    "transforming growth factor alpha receptor",
    "transforming growth factor-alpha receptor",
    "transforming-growth factor alpha receptor",
    "urogastrone receptor"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "receptor protein-tyrosine kinase",
    "peptide receptors",
    "gastrointestinal hormone receptors",
    "epidermal growth factor"
  ],
  "references": [
    "Medical Subject Headings 2014",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "receptores del factor de crecimiento epidérmico"
  },
  "url": "https://mlchart.com/terminology/agriculture/epidermal-growth-factor-receptors/"
}