erbB-2 receptor

{
  "id": "MLC-T-AGR-002268",
  "term": "erbB-2 receptor",
  "field": "Agriculture and food",
  "definition": "A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (epidermal growth factor receptor), the erbB-3 receptor and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.",
  "synonyms": [
    "HER-2 proto-oncogene protein",
    "c-erbB-2 protein",
    "c-erbB2 receptor",
    "c-neu proto-oncogene protein",
    "erbB-2 proto-oncogene protein",
    "erbB-2 receptor protein-tyrosine kinase",
    "human epidermal growth factor receptor-2",
    "neu receptor",
    "proto-oncogene protein HER-2",
    "proto-oncogene protein c-neu",
    "proto-oncogene proteins c-erbB-2"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "receptor protein-tyrosine kinase"
  ],
  "references": [
    "Medical Subject Headings 2014",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "receptor erbB-2"
  },
  "url": "https://mlchart.com/terminology/agriculture/erbb-2-receptor/"
}