Haploinsufficiency

{
  "id": "MLC-T-AGR-003042",
  "term": "Haploinsufficiency",
  "field": "Agriculture and food",
  "definition": "A copy number variation that results in reduced gene dosage due to any loss-of-function mutation. The loss of heterozygosity is associated with abnormal phenotypes or diseased states because the remaining gene is insufficient.",
  "subject": "Natural Resources, Conservation, Environment",
  "see_also": [
    "loss of heterozygosity",
    "gene dosage",
    "loss-of-function mutation",
    "copy number variation"
  ],
  "references": [
    "Medical Subject Headings",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "haploinsuficiencia"
  },
  "url": "https://mlchart.com/terminology/agriculture/haploinsufficiency/"
}