Loss of heterozygosity

{
  "id": "MLC-T-AGR-003846",
  "term": "Loss of heterozygosity",
  "field": "Agriculture and food",
  "definition": "The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal hemizygosity. It is detected when heterozygous markers for a locus appear monomorphic because one of the alleles was deleted.",
  "synonyms": [
    "allelic loss"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "allelic imbalance",
    "chromosome elimination",
    "heterozygosity",
    "haploinsufficiency"
  ],
  "references": [
    "Medical Subject Headings",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "pérdida de heterocigosidad"
  },
  "url": "https://mlchart.com/terminology/agriculture/loss-of-heterozygosity/"
}