Insulin receptor substrate proteins

{
  "id": "MLC-T-AGR-003465",
  "term": "Insulin receptor substrate proteins",
  "field": "Agriculture and food",
  "definition": "A structurally-related group of signaling proteins that are phosphorylated by the insulin receptor protein-tyrosine kinase. The proteins share an N-terminal pleckstrin homology domain, a phosphotyrosine-binding domain that interacts with the phosphorylated insulin receptor, and a C-terminal tyrosine-rich domain. Upon tyrosine phosphorylation, insulin receptor substrate proteins interact with specific SH2 domain containing proteins that are involved in insulin receptor signaling.",
  "subject": "Fields of Study",
  "see_also": [
    "signal transducing adaptor proteins",
    "insulin receptors"
  ],
  "references": [
    "Medical Subject Headings 2017",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "proteínas del sustrato receptor de insulina"
  },
  "url": "https://mlchart.com/terminology/agriculture/insulin-receptor-substrate-proteins/"
}