Base excision repair

{
  "id": "MLC-T-ENV-002764",
  "term": "Base excision repair",
  "field": "Environment",
  "term_source": "Base Excision Repair",
  "definition": "Initiation of DNA base excision repair (BER) involves a DNA glycosylase that binds the altered deoxynucleoside in an extrahelical position and catalyzes cleavage of the base-sugar bond. Subsequently, an AP endonuclease or AP lyase activity incises the abasic site, followed by short-patch gap-filling, excision of the base-free sugar-phosphate residue, and ligation.",
  "abbreviation": "BER",
  "subject": "Biological substances",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/base-excision-repair/"
}