DNA interstrand cross-link repair

{
  "id": "MLC-T-ENV-008334",
  "term": "DNA interstrand cross-link repair",
  "field": "Environment",
  "term_source": "DNA Interstrand Cross-Link Repair",
  "definition": "DNA interstrand cross-links (ICLs) are very toxic to dividing cells, because they induce mutations, chromosomal rearrangements and cell death. A number of multi-step DNA repair pathways including nucleotide excision repair, homologous recombination and post-replication/translesion repair all impinge on their repair.",
  "subject": "Biological substances",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/dna-interstrand-cross-link-repair/"
}