Blood-brain barrier

{
  "id": "MLC-T-ENV-003467",
  "term": "Blood-brain barrier",
  "field": "Environment",
  "term_source": "Blood-Brain Barrier",
  "definition": "1. A network of blood vessels with closely spaced cells that makes it difficult for potentially toxic substances (such as anticancer drugs) to penetrate the blood vessel walls and enter the brain.\n\n2. A naturally occurring barrier created by the modification of brain capillaries (as by reduction in fenestration and formation of tight cell-to-cell contacts) that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues.",
  "abbreviation": "BBB",
  "subject": "Biological substances",
  "references": [
    "NIH Genetics Home Reference Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/blood-brain-barrier/"
}