Chronic Reference Dose

{
  "id": "MLC-T-ENV-004997",
  "term": "Chronic Reference Dose",
  "field": "Environment",
  "definition": "An estimate (with uncertainty spanning perhaps an order of magnitude) of a daily oral exposure for a chronic duration (up to a lifetime) to the human population (including sensitive subgroups) that is likely to be without an appreciable risk of deleterious effects during a lifetime. It can be derived from a NOAEL, LOAEL, or benchmark dose, with uncertainty factors generally applied to reflect limitations of the data used. Generally used in EPA's noncancer health assessments.",
  "abbreviation": "Chronic RfD",
  "subject": "Health and safety",
  "references": [
    "Integrated Risk Information System (IRIS) Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/chronic-reference-dose/"
}