Contact hypersensitivity

{
  "id": "MLC-T-ENV-006301",
  "term": "Contact hypersensitivity",
  "field": "Environment",
  "term_source": "Contact Hypersensitivity",
  "definition": "Contact hypersensitivity is an inflammatory response induced by antigen-reactive T cells that are exposed to antigen on the skin surface (epidermis). Poison ivy is a frequent cause of such reactivity, due to the urushiol from the plant, as are a variety of antigens derived from industrial exposure (e.g. rubber, chromate, nickel). These antigens induce the appearance of Th1-like T cells, which presumably produce IFN to activate macrophages.",
  "subject": "Biological substances",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/contact-hypersensitivity/"
}