Elongation by Telomerase

{
  "id": "MLC-T-ENV-009248",
  "term": "Elongation by Telomerase",
  "field": "Environment",
  "definition": "Most telomeres are maintained by telomerase. The enzymatic activity of telomerase lengthens terminal regions of eukaryotic telomeric DNA by RNA-templated addition of repeated DNA sequences to compensate for sequence loss as the cells divide. Telomerase specifically elongates the 3-prime end of a single-stranded overhang region on the G-rich 3-prime strand while the C-rich strand can be filled in by DNA polymerases. (NCI)",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/elongation-by-telomerase/"
}