MLchartDataset catalogue

Telomere Recombination

Term · Environment · MLC-T-ENV-027769

Recombination can lead to the net elongation of telomeres. The sequence at the ends of chromosomes is highly repetitive and is identical on all telomeres in a given species. The 3-prime end of one chromosome can invade a second chromosome and use the sequence of the second chromosome as a template for telomere elongation by DNA polymerase. The lagging strand can then be filled in by conventional replication mechanisms.

Table 1. Record
IdentifierMLC-T-ENV-027769
FieldEnvironment
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ENV-027769",
  "term": "Telomere Recombination",
  "field": "Environment",
  "definition": "Recombination can lead to the net elongation of telomeres. The sequence at the ends of chromosomes is highly repetitive and is identical on all telomeres in a given species. The 3-prime end of one chromosome can invade a second chromosome and use the sequence of the second chromosome as a template for telomere elongation by DNA polymerase. The lagging strand can then be filled in by conventional replication mechanisms.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/telomere-recombination/"
}

Record 27,769 of 30,736 in Environment terminology (MLC-0121). Request the full dataset.