Gene Amplification

{
  "id": "MLC-T-ENV-012145",
  "term": "Gene Amplification",
  "field": "Environment",
  "definition": "1. Any DNA sequence rearrangement that results in the gain of one or more copies of a DNA segment that contains at least one gene.\n\n2. An increase in the number of copies of a gene. There may also be an increase in the RNA and protein made from that gene. Gene amplification is common in cancer cells, and some amplified genes may cause cancer cells to grow or become resistant to anticancer drugs. Genes may also be amplified in the laboratory for research purposes.",
  "references": [
    "National Cancer Institute Thesaurus",
    "National Cancer Institute Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/gene-amplification/"
}