Limit of Quantification

{
  "id": "MLC-T-ENV-015784",
  "term": "Limit of Quantification",
  "field": "Environment",
  "definition": "1. LOQ is the point at which \"measurements become quantitatively meaningful\".\n\n2. It is the lowest pesticide residue that can be accurately quantitated in a reproducible fashion. The LOQ can be defined in a number of ways, such as the background response plus ten times the standard deviation of the lowest measurable concentration, ten times the signal-to-noise ratio of the baseline noise, ten times the standard deviation of the lowest measurable concentration, etc. In practice, the LOQ is the lowest fortification level that shows adequate recovery during the method validation process.\n\n3. LOQ is the point at which \"measurements become quantitatively meaningful\". [Taylor 1987]\n\n4. It is the lowest pesticide residue that can be accurately quantitated in a reproducible fashion. The LOQ can be defined in a number of ways, such as the background response plus ten times the standard deviation of the lowest measurable concentration, ten times the signal-to-noise ratio of the baseline noise, ten times the standard deviation of the lowest measurable concentration, etc. In practice, the LOQ is the lowest fortification level that shows adequate recovery during the method validation process. [EPA 1998b]\n\n5. The smallest amount of the pesticide that can be quantified by the analytical method. [OECD 1997]\n\n6. Lowest amount of analyte that can be measured with acceptable precision and accuracy as required by data quality objectives.",
  "abbreviation": "LOQ",
  "subject": "Science and research",
  "references": [
    "Taylor 1987",
    "EPA 1998b",
    "Thesaurus of Terms Used in Microbial Risk Assessment",
    "FEM Document Number 2012-01"
  ],
  "url": "https://mlchart.com/terminology/environment/limit-of-quantification/"
}