Oral Slope Factor

{
  "id": "MLC-T-ENV-019744",
  "term": "Oral Slope Factor",
  "field": "Environment",
  "definition": "1. An upper bound, approximating a 95% confidence limit, on the increased cancer risk from a lifetime oral exposure to an agent. This estimate, usually expressed in units of proportion (of a population) affected per mg/kg-day, is generally reserved for use in the low-dose region of the dose-response relationship, that is, for exposures corresponding to risks less than 1 in 100.\n\n2. The Oral Slope Factor represents the upper-bound (approximating a 95 percent confidence limit) estimate of the slope of the dose-response curve in the low-dose region for carcinogens. The units of the slope factor are usually expressed as (mg/kg-day)⁻¹.\n\n3. Represents the upper-bound (approximating a 95 percent confidence limit) estimate of the slope of the dose-response curve in the low-dose region for carcinogens. The units of the slope factor are usually expressed as (mg/kg-day)⁻¹.",
  "subject": "Health and safety",
  "references": [
    "Integrated Risk Information System (IRIS) Glossary",
    "Risk-Screening Environmental Indicators (RSEI) Glossary",
    "Risk-Screening Environmental Indicators Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/oral-slope-factor/"
}