Cancer Slope Factor

{
  "id": "MLC-T-ENV-004044",
  "term": "Cancer Slope Factor",
  "field": "Environment",
  "definition": "1. An upper bound, approximating a 95% confidence limit, on the increased cancer risk from a lifetime exposure to an agent. This estimate, usually expressed in units of proportion (of a population) affected per mg/kg/day, is generally reserved for use in the low-dose region of the dose-response relationship, that is, for exposures corresponding to risks less than 1 in 100.\n\n2. An upper bound (approximating a 95% confidence limit) on the increased cancer risk from a lifetime exposure to an agent. This estimate, usually expressed in units of proportion (of a population) affected per mg/kg/day, is generally reserved for use in the low-dose region of the dose-response relationship; that is, for exposures corresponding to risks less than 1 in 100. This term is usually used to refer to oral slope factors (i.e., slope factors used for assessing ingestion exposure).",
  "abbreviation": "CSF",
  "subject": "Health and safety",
  "see_also": [
    "Cancer Potency"
  ],
  "references": [
    "Community-Based Air Pollution Projects Glossary",
    "EPA 2004"
  ],
  "url": "https://mlchart.com/terminology/environment/cancer-slope-factor/"
}