Significant Adverse Environmental Effect

{
  "id": "MLC-T-ENV-025542",
  "term": "Significant Adverse Environmental Effect",
  "field": "Environment",
  "definition": "Injury to the environment by a chemical substance which reduces or adversely affects the productivity, utility, value, or function of biological, commercial, or agricultural resources, or which may adversely affect a threatened or endangered species. A substance will be considered to have the potential for significant adverse environmental effects if it has one of the following:(1) An acute aquatic EC50 of 1 mg/L or less.(2) An acute aquatic EC50 of 20 mg/L or less where the ratio of aquatic vertebrate 24-hour to 48-hour EC50 is greater than or equal to 2.0.(3) A Maximum Acceptable Toxicant Concentration (MATC) of less than or equal to 100 parts per billion (100 ppb).(4) An acute aquatic EC50 of 20 mg/L or less coupled with either a measured bioconcentration factor (BCF) equal to or greater than 1,000x or in the absence of bioconcentration data a log P value equal to or greater than 4.3.",
  "references": [
    "40 CFR 721.3 (CFR 2013)"
  ],
  "url": "https://mlchart.com/terminology/environment/significant-adverse-environmental-effect/"
}