Toxicity Pathways

{
  "id": "MLC-T-ENV-028407",
  "term": "Toxicity Pathways",
  "field": "Environment",
  "definition": "The 2007 NRC report on Toxicity Testing in the 21st Century envisioned that new technologies will help us to better understand how chemicals perturb normal biological function, and thus identify toxicity pathways. Potential toxic effects of chemicals would be predicted based upon in vitro bioactivity profiles derived from a chemical's effects on cellular molecules and processes. The interpretation of chemically-induced perturbations in toxicity pathways will depend upon linking in vitro effects with adverse outcomes in vivo, and on computer modeling that extrapolates to predicted responses in whole tissues, organisms and populations based on realistic human or environmental exposures.",
  "subject": "Chemicals, toxics and pesticides",
  "references": [
    "Toxicity Testing and Risk Assessment Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/toxicity-pathways/"
}