Tumor progression

{
  "id": "MLC-T-ENV-028866",
  "term": "Tumor progression",
  "field": "Environment",
  "term_source": "Tumor Progression",
  "definition": "1. Under the Armitage-Doll multistage theory of cancer development, the transition of a cell line between the stages which lead to cancer.\n\n2. A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm.",
  "subject": "Health and safety",
  "references": [
    "Integrated Risk Information System (IRIS) Glossary",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/tumor-progression/"
}