anti-HER2 antibody conjugated natural killer cells ACE1702

{
  "id": "MLC-T-ONC-010734",
  "term": "anti-HER2 antibody conjugated natural killer cells ACE1702",
  "field": "Oncology and biomedicine",
  "definition": "An off-the-shelf preparation of natural killer (NK) cells conjugated to a monoclonal antibody targeting human epidermal growth factor receptor 2 (EGFR2; HER2; ErbB2), with potential antineoplastic activity. Upon administration of anti-HER2 antibody conjugated natural killer cells ACE1702, the antibody moiety targets and binds to HER2 on tumor cells, which may lead to cell lysis of HER2-expressing tumor cells by the NK cells. HER2, a tyrosine kinase receptor, is overexpressed by many cancer cell types.",
  "synonyms": [
    "anti-HER2 antibody conjugated NK cells ACE1702",
    "anti-HER2 antibody natural killer cell conjugate ACE1702",
    "anti-HER2 conjugated NK cells ACE1702",
    "anti-HER2 NK cells ACE1702",
    "anti-HER2 NK cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-her2-antibody-conjugated-natural-killer-cells-ace1702/"
}