arginase-1 peptide vaccine

{
  "id": "MLC-T-ONC-011226",
  "term": "arginase-1 peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A vaccine comprised of arginase-1 peptides, with potential antineoplastic activity. Upon vaccination, the arginase-1 peptide vaccine may activate the immune system to induce an immune response against arginase-1-expressing cells. Arginase-1 is expressed by some cancer cells and by immune inhibitory cells, such as myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs); its expression is associated with poor prognosis.",
  "synonyms": [
    "ARG-1 peptide vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/arginase-1-peptide-vaccine/"
}