MLchartDataset catalogue

atrasentan hydrochloride

Term · Oncology and biomedicine · MLC-T-ONC-011288

The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.

Table 1. Record
IdentifierMLC-T-ONC-011288
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-011288",
  "term": "atrasentan hydrochloride",
  "field": "Oncology and biomedicine",
  "definition": "The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/atrasentan-hydrochloride/"
}

Record 2,572 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.