Autologous anti-gp100:154-162 TCR tumor infiltrating lymphocytes

{
  "id": "MLC-T-ONC-011439",
  "term": "Autologous anti-gp100:154-162 TCR tumor infiltrating lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for the amino acid 154 through 162 of the melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activities. Upon intravenous administration, the autologous anti-gp100:154-162 TCR TILs may recognize and halt the growth of gp100-expressing melanoma cells.",
  "synonyms": [
    "autologous anti-gp 100:154-162 TCR TILs",
    "autologous anti-gp100:154-162 TCR gene engineered TILs",
    "autologous anti-gp100:154-162 TCR gene-engineered tumor infiltrating lymphocytes",
    "autologous anti-gp100:154-162 TCR TILs",
    "autologous anti-gp100:154-162 TCR-engineered TILs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-anti-gp100-154-162-tcr-tumor-infiltrating-lymphocytes/"
}