Autologous anti-MART-1 F5 TCR tumor infiltrating lymphocytes

{
  "id": "MLC-T-ONC-011470",
  "term": "Autologous anti-MART-1 F5 TCR tumor infiltrating lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for an epitope of MART-1 (F5 TCR), with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-MART-1 F5 TCR TILs may recognize and halt the growth of MART-1-expressing melanoma cells.",
  "synonyms": [
    "autologous anti-MART-1 F5 TCR gene-engineered TILs",
    "autologous anti-MART-1 F5 TCR gene-engineered tumor infiltrating lymphocytes",
    "autologous anti-MART-1 F5 TCR TILs",
    "autologous anti-MART-1 F5 TCR-engineered TILs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-anti-mart-1-f5-tcr-tumor-infiltrating-lymphocytes/"
}