anti-MART-1 TCR retroviral vector-transduced autologous TIL

{
  "id": "MLC-T-ONC-010877",
  "term": "anti-MART-1 TCR retroviral vector-transduced autologous TIL",
  "field": "Oncology and biomedicine",
  "definition": "Human tumor infiltrating lymphocytes (TIL) isolated from a melanoma patient and were engineered to react with the melanoma antigen MART-1 (Melanoma Antigen Recognized by T cells, also called Melan-A). These TILs are transfected with a retroviral vector encoding anti-MART-1 specific T-cell receptors, grown in culture, and then transferred back to the patient. These genetically modified TIL may recognize and halt the growth of MART-1-expressing melanoma cells.",
  "synonyms": [
    "MSGV1AIB (anti-MART-1 TCR) retroviral vector-transduced autologous TIL"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-mart-1-tcr-retroviral-vector-transduced-autologous-til/"
}